Additional information
| Active substance | Isotretinoin  | 
		
|---|---|
| Active Half-Life | 20-22 hours  | 
		
| Classification | Dermatotropic drug  | 
		
| Dosage | 10-40 mg/day  | 
		
| Acne | No  | 
		
| Water Retention | No  | 
		
| HBR | No  | 
		
| Hepatotoxicity | Yes  | 
		
| Aromatization | No  | 
		
| Lab Test | Liver function tests, lipid profiles, pregnancy tests  | 
		
| Also known as | 13-cis-Retinoic acid  | 
		
| WAREHOUSE | International Warehouse 2  | 
		
| Blood pressure | No significant effect  | 
		
| Trade name | Accutane, Roaccutane, Claravis, others  | 
		
| Storage conditions | Store at controlled room temperature (15-30В°C), protect from light  | 
		
| Chemical name | (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid  | 
		
| Formula | C20H28O2  | 
		
| Substance class | Retinoid  | 
		
| Main action | Reduces sebum production, corrects abnormal keratinization, has anti-inflammatory properties  | 
		
| Half-life | 10-20 hours  | 
		
| Dosage (medical) | Typically 0.5 to 1 mg per kg of body weight per day, taken in two divided doses  | 
		
| Dosage (sports) | Not applicable  | 
		
| Effects | Reduces acne, decreases sebum production, promotes skin renewal  | 
		
| Side effects | Dry skin, lips and eyes, itching, nosebleeds, muscle aches, sensitivity to sunlight, decreased night vision, potentially severe birth defects if taken during pregnancy  | 
		
| Use in sports | None  | 
		
| Manufacturer | Teva  | 
		





                        
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